Coumarins and derivatives
Sigma Organic Chemistry 3-Acetylcoumarin | 5G | 3949-36-8 | MFCD00006853
CAS #: 3949-36-8
MDL #: MFCD00006853
Purity: >96 %
UNSPSC Code: 12352100
Molecular Weight: 188.18
Sigma Organic Chemistry 3-(Ethylamino)-p-cresol | 5G | 120-37-6 | MFCD00002382
CAS #: 120-37-6
MDL #: MFCD00002382
Purity: >90%
UNSPSC Code: 12352100
Molecular Weight: 151.21
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin >=98% | 531-59-9 | MFCD00006876 |
7-Methoxycoumarin >=98% | Purity: >=98% | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 |
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin suitable for fluorescence, >=98.0% (TLC) | 531-59-9 | MFCD00006876 | 100MG
7-Methoxycoumarin suitable for fluorescence, >=98.0% (TLC) | Purity: >=98.0% (TLC) | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 | 100MG
Sigma Aldrich Fine Chemicals Biosciences Esculin hydrate >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Esculin hydrate >=98.0% (HPLC) | Purity: >=98.0% (HPLC) | 531-75-9 (anhydrous) | MFCD00149492 | 10G
Apexbio Technology LLC 6,7-Dihydroxycoumarin 305-01-1 20mg
6 7-Dihydroxycoumarin (CAS 305-01-1) also known as esculetin is a naturally occurring coumarin derivative extracted from Aesculus hippocastanum Linn This compound exhibits notable antioxidant activity primarily by scavenging reactive oxygen species and inhibiting lipid peroxidation Additionally 6 7-dihydroxycoumarin has been studied for its modulatory effects on various cellular signaling pathways implicated in inflammation and apoptosis Its applications in biomedical research include investigations into oxidative stress inflammation and related disease models The compound is soluble in ethanol and dilute alkali and should be stored in a sealed cool and dry environment to preserve stability
Apexbio Technology LLC 7-Amino-4-(trifluoromethyl)coumarin 53518-15-3 100mg
7-Amino-4-trifluoromethyl coumarin (CAS 53518-15-3) is a small-molecule antagonist targeting serotonin receptor subtype 1E (HTR1E) galanin receptor 2 (GALR2) and gamma receptor subtype 2 (GalR2) It is designed to antagonize these receptors thereby modulating receptor-mediated signaling pathways 7-Amino-4-trifluoromethyl coumarin exerts its biological activity primarily through receptor antagonism and inhibition of hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4) enzymatic activity In biochemical assays it demonstrates inhibitory activity toward HSD17B4 with reported bioactivity at approximately 21 M Based on these pharmacological properties 7-Amino-4-trifluoromethyl coumarin holds research potential in the investigation of protease activity receptor-mediated signaling and metabolic enzyme regulation
Apexbio Technology LLC Coumarin 6 38215-36-0 50mg
Coumarin 6 (CAS 38215-36-0) is a fluorescent dye utilized primarily as a tracer in biomedical research for particulate drug delivery systems Coumarin 6 facilitates the visualization and analysis of particle distribution trafficking and cellular uptake processes in vitro and in vivo It is applied to study biological mechanisms related to transport and localization of therapeutic molecules and their interactions with cellular compartments Based on these properties Coumarin 6 holds research potential in evaluating drug delivery dynamics cellular internalization pathways pharmacokinetic behavior and disease-related investigations
Apexbio Technology LLC Palomid 529 914913-88-5 50mg
Palomid 529 (CAS 914913-88-5) is a small-molecule inhibitor of the PI3K/Akt/mTOR signaling pathway targeting both TORC1 and TORC2 complexes It exhibits potent anti-proliferative activity in the NCI-60 cell line panel with GI50 values below 35 M In endothelial cell assays Palomid 529 inhibits VEGF- and bFGF-induced proliferation with IC50 values of 20 nM and 30 nM respectively The PI3K/Akt/mTOR pathway is implicated in tumor cell survival proliferation angiogenesis and resistance to apoptosis Palomid 529 has also demonstrated the ability to suppress radiation-induced expression of Id-1 VEGF MMP-2 and MMP-9 expanding its utility in studies of cancer biology and radiotherapy sensitization
Sigma Organic Chemistry 8-Acetyl-7-hydroxycouma | 1G | 6748-68-1 | MFCD00270162
8-Acetyl-7-hydroxycouma , 1G
About this item:
CAS #: 6748-68-1
MDL #: MFCD00270162
Purity: ≥97
Molecular Weight: 204.18
UNSPSC Code: 12352100
eMolecules Coumarin-6-carboxaldehyde | 51690-26-7 | MFCD01941322 | 1g
Apollo Scientific | Coumarin-6-carboxaldehyde | 1g | 562441556 | OR8856 | 95.000 | 51690-26-7 | MFCD01941322 | 174.155 | C10H6O3
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TARGETMOL CHEMICALS INC Daphnetin 50MG
Also available in 1 mL, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50 7.67 uM), PKA (IC50 9.33 uM), and PKC (IC50 25.01 uM), also exhibit anti-oxidant and anti-inflammatory activities. Purity 99.82%